Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11013420 | Journal of Affective Disorders | 2019 | 7 Pages |
Abstract
It is suggested that persistent inflammation is associated with reduction of hippocampal and gray matter volumes in older patients with BD. This phenomenon is supported by increases in sTNF-R1, sIL-2R, and IL-1β levels. Neuroinflammation due to aging, obesity, and BD pathophysiology may play a role in BD neuroprogression across the life span.
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Authors
Shang-Ying Tsai, Ariel G. Gildengers, Jung-Lung Hsu, Kuo-Hsuan Chung, Pao-Huan Chen, Yu-Jui Huang,