| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11013451 | Biological Psychiatry | 2018 | 49 Pages |
Abstract
Our findings provide novel evidence for the dysconnection hypothesis by showing that during complex real-life-like stimulation, the most prominent functional alterations in psychotic disorders relate to integrative brain functions. Presence of such abnormalities in first-episode psychosis rules out long-term effects of illness or medication. These methods can be used in further studies to map widespread hub alterations in a single functional magnetic resonance imaging session and link them to potential downstream and upstream pathways.
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Biological Psychiatry
Authors
Teemu Mäntylä, Lauri Nummenmaa, Eva Rikandi, Maija Lindgren, Tuula Kieseppä, Riitta Hari, Jaana Suvisaari, Tuukka T. Raij,