| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11014640 | Journal of Allergy and Clinical Immunology | 2018 | 23 Pages |
Abstract
TRIM21 plays a protective role in mucosal inflammation through inhibiting TH1 and TH17Â cell differentiation. Thus TRIM21 might serve as a potential therapeutic target for the treatment of IBDs.
Keywords
TRIMActive ulcerative colitisRetinoic acid–related orphan receptor γt2-MERAG1Th1RORγtTNBSCDAINF-κBIRF3Th17IBDqRT-PCR2-mercaptoethanolquantitative RT-PCRTrinitrobenzene sulfonic acidMucosal inflammationCrohn diseaseInflammatory bowel diseaseTALENCD4+ T cellsCrohn's Disease Activity IndexInterferon regulatory factor 3nuclear factor κBLamina propriaSystemic lupus erythematosusSLEHealthy control subjectwild-typeRecombination-Activating GeneUlcerative colitis
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Authors
Guangxi PhD, Wei PhD, Lin MS, Tianming MD, Wenjing PhD, Ping PhD, Xiaoping PhD, Yingzi PhD, Zhanju MD, PhD,