Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11015039 | International Journal of Cardiology | 2018 | 31 Pages |
Abstract
Collectively, our data identify JNK-dependent upregulation of BNIP3 as a critical process involved in ER stress-induced cardiomyocyte contractile dysfunction and highlight 4PBA as a potential intervention to counteract ER stress-mediated BNIP3 upregulation in failing hearts.
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Authors
Luiz H.M. Bozi, Ana P.C. Takano, Juliane C. Campos, Natale Rolim, Paulo M.M. Dourado, Vanessa A. Voltarelli, Ulrik Wisløff, Julio C.B. Ferreira, Maria L.M. Barreto-Chaves, Patricia C. Brum,