Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11018389 | Acta Tropica | 2019 | 27 Pages |
Abstract
Bluetongue (BT) is a vector-borne disease of immense economic importance for small and large ruminants. Despite frequent disease reports from neighboring countries, a little is known about current disease status and prevalent serotypes in Pakistan. We screened a total of 1312 healthy animals for group-specific antibodies and serotype-specific genome for BT virus through competitive ELISA and real-time PCR, respectively. An overall prevalence of group-specific VP7 antibodies [28.81% (nâ=â378/1312, 95% CIâ=â26.4-31.4)] was observed. The prevalence was higher in goats [40.75% (nâ=â194/476, 95% CIâ=â36.4-45.3)] followed by buffalo [29.34% (nâ=â81/276, 95% CIâ=â24.3-34.9)], sheep [18.40% (nâ=â60/326, 95% CIâ=â14.5-22.9)] and cattle [17.94% (nâ=â42/234, 95% CIâ=â13.56-23.4)]. The odds of seropositivity were more in buffalo of Nili breed (ORâ=â2.06, 95% CIâ=â1.19-3.58) as well as those found with a presence of vector (ORâ=â2.04, 95% CIâ=â1.16-3.59). Buffalo and cattle with history of abortion [(ORâ=â3.95, 95% CIâ=â1.33-11.69) and (ORâ=â5.89, 95% CIâ=â1.80-19.27) respectively] were much likely to be infected with the disease. Serotype 8 was detected in all animal species while, serotypes 4 and 6 were detected in sheep, 2, 6 and 11 in goat, and 2 and 16 in buffalo. The study concludes a much frequent exposure of different serotypes of Bluetongue virus (BTV) in small and large ruminants and indicates its expansion to enzootic range worldwide.
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Authors
Tayyebah Sohail, Tahir Yaqub, Tariq Abbas, Masood Rabbani, Jawad Nazir, Syeda Marriam Maqbool, Saima Yaqub, Momena Habib, Aziz ul-Rahman, Nadia Mukhtar, Muhammad Shahbaz, Muhammad Yasir Zahoor, Muhammad Zubair Shabbir,