| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11018478 | Journal of Microbiology, Immunology and Infection | 2018 | 6 Pages |
Abstract
Favipiravir as a chain terminator would not be incorporated and replicate to cause lethal mutagenesis as a mutagen like ribavirin, and resistant mutants were not isolated. A high replication level would generate mutations leading to favipiravir resistance as ribavirin resistance was generated, but generated mutations would be lethal to the RNA polymerase function.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Tohru Daikoku, Mineyuki Mizuguchi, Takayuki Obita, Takeshi Yokoyama, Yoshihiro Yoshida, Masaya Takemoto, Kimiyasu Shiraki,