Article ID Journal Published Year Pages File Type
11018478 Journal of Microbiology, Immunology and Infection 2018 6 Pages PDF
Abstract
Favipiravir as a chain terminator would not be incorporated and replicate to cause lethal mutagenesis as a mutagen like ribavirin, and resistant mutants were not isolated. A high replication level would generate mutations leading to favipiravir resistance as ribavirin resistance was generated, but generated mutations would be lethal to the RNA polymerase function.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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