| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11019486 | Egyptian Journal of Medical Human Genetics | 2018 | 5 Pages |
Abstract
DNMT3A R882H is a frequent mutation in adult de novo AML. The frequency of the mutation tends to increase with age. The two methods used in the study are easy to interpret and are recommended for rapid detection of the mutation required for risk stratification.
Keywords
French American BritishAMLFLT3-ITDMPNWBCMDSDFSNPM1DNMT3ACMMLDNA methyltransferaseDisease free survivaloverall survivalcomplete remissionPCR-RFLPMyelodysplastic syndromesFabchronic myelomonocytic leukemiabone marrowMyeloproliferative neoplasmsHemoglobinHgbpolymerase chain reaction restriction fragment length polymorphismwhite blood cells
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Authors
Ghada M. Elsayed, Abd Elgawad A. Fahmi, Nevine F. Shafik, Reham A.A. Elshimy, Heba K. Abd Elhakeem, Sara A. Attea,