Article ID Journal Published Year Pages File Type
11021813 Brain Research 2019 30 Pages PDF
Abstract
PD patients had reduced serum BDNF levels compared to HC, regardless of presence of co-morbid depression. PD is at least equally effective in reducing serum BDNF levels as depression. Motor progression predicts serum BDNF downregulation in PD. Acute exercise improves motor function and depressive symptoms in PD probably via BDNF upregulation. The paradoxical rise in serum BDNF in advance PD is probably compensatory in nature.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
Authors
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