Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11022512 | Molecular Metabolism | 2018 | 12 Pages |
Abstract
Activation of Tas2r108 in the gut results in a remodeling of enteroendocrine hormone release and bile acid metabolism that ameliorates multiple features of metabolic syndrome. Targeting extraoral bitter taste receptors may be useful in metabolic disease.
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Authors
Bernard P. Kok, Andrea Galmozzi, Nicole K. Littlejohn, Verena Albert, Cristina Godio, Woojoo Kim, Sean M. Kim, Jeffrey S. Bland, Neile Grayson, Mingliang Fang, Wolfgang Meyerhof, Gary Siuzdak, Supriya Srinivasan, Maik Behrens, Enrique Saez,