Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11022517 | Molecular Metabolism | 2018 | 11 Pages |
Abstract
We report that systemic loss of TBK1 kinase function has an overall protective effect on metabolic readouts in mice on an obesogenic diet, which is mediated by loss of an inhibitory interaction between TBK1 and the insulin receptor.
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Authors
Victoria H. Cruz, Emily N. Arner, Katherine W. Wynne, Philipp E. Scherer, Rolf A. Brekken,