| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11023077 | Life Sciences | 2018 | 10 Pages |
Abstract
These results indicate that celastrol could be a potent anti-inflammatory agent and a natural AMPK enhancer. However, celastrol has only modest effects on renal cystogenesis and has a narrow therapeutic window. Further studies are needed to clarify whether celastrol has the potential for the treatment of ADPKD.
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Authors
Ming-Yang Chang, Chun-Yih Hsieh, Chan-Yu Lin, Tai-Di Chen, Huang-Yu Yang, Kuan-Hsing Chen, Hsiang-Hao Hsu, Ya-Chung Tian, Yung-Chang Chen, Cheng-Chieh Hung, Chih-Wei Yang,