Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11025329 | Journal of Affective Disorders | 2019 | 7 Pages |
Abstract
Among individuals with treatment-resistant depression, QoL is lowest in the psychological and physical domains. QoL is only modestly correlated with patient-rated symptoms and functioning, and even more weakly correlated with clinician-rated scales, indicating that measures of symptoms and functioning cannot serve as QoL proxies. QoL should be assessed when caring for patients with treatment-resistant depression. When developing novel biological, psychological, and social interventions for treatment-resistant depression, QoL should be targeted as a distinct clinical outcome.
Keywords
ECTMGHCGI-SSF-36PHQ-9TRDHDRSGAFACEQOLQuality of lifeWHOQOL-BrefMajor depressive disorderbipolar disorderFunctional impairmentGlobal Assessment of FunctioningTreatment-resistant depressionMassachusetts General HospitalElectroconvulsive therapychildhood adversity36-Item Short Form Health SurveyWork and social adjustment scaleHamilton Depression Rating ScalePatient Health Questionnaire
Related Topics
Health Sciences
Medicine and Dentistry
Psychiatry and Mental Health
Authors
Heidemarie Lex, Yarden Ginsburg, Adam F. Sitzmann, Clara Grayhack, Daniel F. Maixner, Brian J. Mickey,