Article ID Journal Published Year Pages File Type
11025540 NeuroImage 2019 15 Pages PDF
Abstract
We have successfully created a small bispecific antibody-based radioligand capable of crossing the BBB, subsequently binding to and visualizing intrabrain Aβ in vivo. The radioligand displayed better sensitivity compared with [11C]PIB, and brain concentrations correlated with soluble neurotoxic Aβ aggregates.
Related Topics
Life Sciences Neuroscience Cognitive Neuroscience
Authors
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