| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11025745 | Antiviral Research | 2018 | 30 Pages |
Abstract
Our results demonstrate that mTOR1-inhibitors are able to reduce early-expression of wildtype and rearranged NCCRs, which might contribute to previously described inhibition of BKPyV-replication. Dual mTOR1/2-inhibitors, however, additionally might shift viral early into late-expression promoting synthesis of viral structural proteins and particle production.
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Authors
Johannes Korth, Olympia E. Anastasiou, Jens Verheyen, Julia Dickow, Helene Sertznig, Nicola Frericks, Barbara Bleekmann, Andreas Kribben, Alexandra Brinkhoff, Benjamin Wilde, Kathrin Sutter, Ulf Dittmer, Sandra Ciesek, Oliver Witzke, Marek Widera,