Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11027130 | European Journal of Medicinal Chemistry | 2018 | 29 Pages |
Abstract
Aiming to develop potent dual PPARs/FFA1 agonists, we have hybrid the Sanofi's FFA1 agonist 1 with PPARδ agonist 2 based on their structural similarity, exemplified by the orally bioavailable FFA1/PPARγ/PPARδ pan agonist 15.306
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zheng Li, Zongtao Zhou, Fengjian Deng, Yuyi Li, Danjun Zhang, Luyong Zhang,