Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity

Physical Sciences and Engineering Chemistry Organic Chemistry

Tetsuya Iida, Minoru Ubukata, Ikuo Mitani, Yuichi Nakagawa, Katsuya Maeda, Hiroto Imai, Yosuke Ogoshi, Takahiro Hotta, Shohei Sakata, Ryuhei Sano, Hisayo Morinaga, Tamotsu Negoro, Shinichi Oshida, Masahiro Tanaka, Takashi Inaba,