Transmission of IMI-2 carbapenemase-producing Enterobacteriaceae from river water to human

Here we have identified for the first time the presence of an IMI-2-producing E. asburiae in a river in the South of France and suggest transmission from the river to a human probably following intestinal translocation. General insights into transmission of CPE from the environment to humans are gained from this case. Considering the rapid spread of CPE in humans, the risk of transfer from an environmental reservoir to human microbiota should be thoroughly investigated at least by implementing environmental surveillance of carbapenem resistance.