Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
11032236 | Journal of Inorganic Biochemistry | 2018 | 33 Pages |
Abstract
Eight new platinum(II) complexes Pt1-Pt8 with substituted 3â(2â²âbenzimidazolyl) coumarins were synthesized and characterized. Pt1 is a telomerase inhibitor targeting c-myc promoter elements and causes mitochondrial dysfunction in the following order: Pt1â¯>â¯Pt2â¯>â¯Pt3.276
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Ting Meng, Qi-Pin Qin, Zhen-Rui Wang, Li-Ting Peng, Hua-Hong Zou, Zhen-Yuan Gan, Ming-Xiong Tan, Kai Wang, Fu-Pei Liang,