| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11032242 | Journal of Inorganic Biochemistry | 2018 | 7 Pages |
Abstract
Amino-decorated nonporous silica nanoparticles were further coated with alginic acid to produce a potential biocompatible delivery system for Pt(IV) antitumor prodrug (OCâ6â44)âacetato(βâalaninato)diamminedichloridoplatinum(IV), through the formation of amide bonds. The conjugate was more active than both cisplatin and the Pt(IV) precursor, due to its more efficient cell uptake.112
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Mauro Ravera, Elisabetta Gabano, Diego Bonzani, Ilaria Zanellato, Aldo Arrais, Simone Cantamessa, Marco Biggiogera, Domenico Osella,