| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 11032244 | Journal of Inorganic Biochemistry | 2018 | 45 Pages |
Abstract
Cadmium (Cd) induced cholesterol exporter ATP-binding cassette transporter A1 (ABCA1) accumulation through inhibiting lysosomal pathways by disrupting its acidic environment of lysosomes and autolysosomes and autophagic flux. And Cd also increased oxysterol-binding protein (OSBP) degradation by increasing ubiquitination. Cd induced ABCA1 accumulation and OSBP degradation facilitated cholesterol excretion.243
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Yanwei Wang, Xingqi Ji, Shuya Dai, Haitao Liu, Dandan Yan, Yang Zhou, Jie Gu, Haifeng Shi,