Low on energy? An energy supply-demand perspective on stress and depression

Article ID	Journal	Published Year	Pages	File Type
11032328	Neuroscience & Biobehavioral Reviews	2018	78 Pages	PDF

Keywords

AMPK NF-κB DBS 5-HT LPS IL-1 EPC CRH AMP ECT CuS NADPH Aβ mTOR ICAM-1 PDE SVD SRI MDD RBC 5-hydroxytryptamine BOLD AMPA FST ADP CBF NMDA N-methyl-d-aspartate AVP EAAT CTh HIF WMH CBV VSMC VCAM-1 Pericyte AT2 OEF Selective serotonin uptake inhibitor Trophic support ACTH BDNF MTT ROS Adenosine Triphosphate ATP adenosine diphosphate adenosine monophosphate Rheumatoid arthritis Forced swimming test amyloid β Angiotensin II ACh white matter hyperintensities Major depressive disorder early life stress chronic unpredictable stress Stress Acetylcholine α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid Arachidonic acid Functional magnetic resonance imaging (fMRI)inflammation MRI interleukin-1 serotonin reuptake inhibitor Alzheimer’s disease Alzheimer’s disease (AD)Cerebral small vessel disease cardiovascular disease deep brain stimulation Magnetic resonance imaging Neuroimaging fMRI functional magnetic resonance imaging long term potentiation LTP Neurodegeneration tumor necrosis factor-α Positron emission tomography cerebral blood flow Cerebral blood volume excitatory amino acid transporters SMA Electroconvulsive therapy mtDNA BBB Serotonin blood oxygen level dependent Vascular smooth muscle cell Endothelial progenitor cell dentate gyrus brain derived neurotrophic factor Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Hypoxia Inducible Factor TNF-α nuclear factor kappa beta Phosphodiesterase locus coeruleus Lipopolysaccharides PVN Blood-brain barrier Cerebrospinal fluid CSF SSRI Intercellular adhesion molecule 1 Vascular cell adhesion molecule 1 Mean transit time HPA noradrenaline Nitric oxide nicotinamide adenine dinucleotide phosphate mammalian target of rapamycin paraventricular nucleus of the hypothalamus Co-morbidity Hemorheology adrenocorticotrophic hormone corticotrophin releasing hormone hypothalamic-pituitary-adrenal Hippocampus Hypoxia arginine vasopressin Blood viscosity Pathophysiology PET C reactive protein CRP Prolyl hydroxylase catecholamines oxygen extraction fraction cortisol AMP-activated kinase Gut red blood cell glutamate Glucocorticoid Glycocalyx Reactive oxygen species glucocorticoid receptor

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Low on energy? An energy supply-demand perspective on stress and depression

Authors

Leif Ãstergaard, Martin Balslev JÃ¸rgensen, Gitte Moos Knudsen,