Odontogenic lesion mimicking squamous cell carcinoma: A new histological entity?

- The diagnosis of odontogenic tumors is complicated due to the heterogeneity of the lesions, representing a continuous spectrum of disease or several different all together, borderline forms, and hybrid forms.
- The lesion described here looked like a squamous cell carcinoma of the alveolar ridge combining histological features of an odontogenic neoplasia, including entities like the squamous odontogenic tumor and clear cell odontogenic carcinoma.
- The surgical assessment of odontogenic tumors is controversial, representing a challenge for surgeons. A persistent dilemma is determinating the malignancy of the lesions. The lesion was framed among odontogenic tumors, suggestive for a co-existence of two different odontogenic entities of which the malignant form degenerated into squamous cell carcinoma, or also of a co-existence, from the beginning, of three different entities independently.