| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1153930 | Statistics & Probability Letters | 2008 | 9 Pages |
Abstract
In clinical trials with time to an event endpoint, the Wald test in a Cox regression model may be used to assess the difference between two treatments. In this paper, a Bartlett type correction to the Wald test is derived and applied to the analysis of data from a clinical trial on actuate myelogenous leukemia (AML). Monte Carlo simulations are also performed to assess the actual type I error and power of the proposed Bartlett corrected test.
Related Topics
Physical Sciences and Engineering
Mathematics
Statistics and Probability
Authors
Xiao Li, Yaohua Wu, Dongsheng Tu,