Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1154270 | Statistics & Probability Letters | 2006 | 7 Pages |
Abstract
We present an adaptive design for multi-arm clinical trials with bounded response and prognostic factors. The allocation is ruled by an urn model that fits a Robbins-Monro scheme. We obtain asymptotic properties for the performance and allocation of treatments.
Related Topics
Physical Sciences and Engineering
Mathematics
Statistics and Probability
Authors
José A. Moler, Fernando Plo, Miguel San Miguel,