Article ID Journal Published Year Pages File Type
1172973 Analytical Biochemistry 2016 7 Pages PDF
Abstract

In this work, a simple electrochemical immunosensor was developed for the detection of carcinoembryonic antigen (CEA) based on rhombic dodecahedral Cu2O nanocrystals–graphene oxide–gold nanoparticles (rCu2O–GO–AuNPs). GO as the template and surfactant resulting in rCu2O exhibit improved rhombic dodecahedral structure uniformity and excellent electrochemical performance. Moreover, GO was found to be able to effectively improve the long stability of rCu2O on the electrode response. Under optimal conditions, the immunosensor showed a low limit of detection (0.004 ng ml−1) and a large linear range (0.01–120 ng ml−1). This work presents a potential alternative for the diagnostic applications of GO-supported special morphology materials in biomedicine and biosensors.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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