| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1176088 | Analytical Biochemistry | 2014 | 6 Pages |
Abstract
Lysophosphatidic acid (LPA) is a bioactive lipid involved in cellular signal transduction. LPA plays a role in both physiological and pathological processes. Elevated levels of LPA are observed in the plasma of patients with epithelial ovarian cancer, indicating its potential as a diagnostic marker. Quantification of total LPA can be performed by radioenzymatic, fluorometric, colorimetric, or immunoezymatic assay. Determination of individual LPA molecular species requires the use of capillary electrophoresis, gas chromatography, thin layer chromatography, liquid chromatography, or a matrix-assisted laser desorption/ionization time-of-flight method connected to an appropriate detection system.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Anna Jesionowska, Elzbieta Cecerska, Barbara Dolegowska,