Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1177458 | Analytical Biochemistry | 2006 | 6 Pages |
Abstract
A novel COOH+ ion implantation-modified indium tin oxide (COOH/ITO) electrode was prepared for the first time and applied for determination of daunomycin (or daunorubicin [DNR]). The electrode showed higher catalytic activity than bare ITO electrode with good reproducibility and stability. The determination condition of linear voltammetry was optimized. A calibration curve was obtained over the range 2.0Â ÃÂ 10â7 to 5.0Â ÃÂ 10â6Â mol/L, with a correlation coefficient of 0.9909 and a limit of detection of 1.0Â ÃÂ 10â7Â mol/L. The selectivity of the electrode was illustrated by determination of DNR in samples prepared of urine. X-ray photoelectron spectroscopy (XPS) analysis results showed that the implanted COOH+ maintained characteristics of organic group -COOH. A field emission-scanning electron microscope (FSEM) result showed that the implanted surface caused defects and partial dislocations and formed many active centers.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
DongMei Gao, JingBo Hu, Meng Yang, QiLong Li,