Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1177514 | Analytical Biochemistry | 2006 | 9 Pages |
Abstract
An approach for fast identification and mapping of transcription factor binding sites within long genomic sequences is proposed. Using this approach, 10 CCCTC-binding factor (CTCF) binding sites were identified within a 1-Mb FXYD5–COX7A1 human chromosome 19 region. In vivo binding of CTCF to these sites was verified by chromatin immunoprecipitation assay. CTCF binding sites were mapped within gene introns and intergenic regions, and some of them contained Alu-like repeated elements.
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Analytical Chemistry
Authors
Anna S. Vetchinova, Sergey B. Akopov, Igor P. Chernov, Lev G. Nikolaev, Eugene D. Sverdlov,