Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1178534 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2006 | 10 Pages |
Abstract
The aim of this review is to present an overview of protein sulfation in the context of ‘modificomics’, i.e. post-translational modification-specific proteome research. In addition to a short introduction to the biology of protein sulfation (part 1), we will provide detailed discussion regarding (i) methods and tools for prediction of protein tyrosine sulfation sites (part 2), (ii) biochemical techniques used for protein sulfation analysis (part 3.1), and (iii) mass spectrometric strategies and methods applied to protein sulfation analysis (part 3.2). We will highlight strengths and limitations of different strategies and approaches (including references), providing a primer for newcomers to protein sulfation analysis.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Flavio Monigatti, Brian Hekking, Hanno Steen,