| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1178865 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2010 | 8 Pages |
Abstract
The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response.
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Analytical Chemistry
Authors
Xiaolei Qiu, Katharine V. Brown, Yehu Moran, Danica Chen,