| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1179959 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2010 | 9 Pages |
Abstract
⺠The bHLH domain is marginally stable and folds upon dimerization. ⺠Binding to DNA promotes folding and stabilization of the bHLH domain. ⺠The Orange domain is a stable helical dimer. ⺠HES-1 recognizes dsDNA with high affinity but with low specificity. ⺠Order/disorder transitions may drive HES-1 homo- and hetero-dimerization.
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Authors
Maristella Coglievina, Corrado Guarnaccia, Alessandro Pintar, Sándor Pongor,