Article ID Journal Published Year Pages File Type
1180876 Chemometrics and Intelligent Laboratory Systems 2012 8 Pages PDF
Abstract

Extended multiplicative signal correction (EMSC) is a model-based preprocessing technique that has been frequently used in vibrational spectroscopy. The framework of EMSC allows, apart from basic preprocessing as baseline correction and normalization, to separate and quantify different types of chemical and physical variations in vibrational spectra. EMSC thus enables the user to study these different effects separately. The aim of this tutorial is to give a comprehensive description of EMSC and its use in vibrational spectroscopy. Examples from FT-IR and Raman spectroscopy of biological materials will be used, and different extensions of EMSC and their properties will be discussed.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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