Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1181542 | Chemometrics and Intelligent Laboratory Systems | 2011 | 7 Pages |
Abstract
The problem of setting the limit of detection is considered for censored samples and heterogeneous errors. After formal definitions of the critical level and of the method detection limit, we obtain simplified maximum likelihood-type estimators. The estimation problem of the truncation parameter and its uncertainty are reviewed. Upper confidence bounds for the limit of detection are derived and some simulation results are given.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Andrew L. Rukhin, Daniel V. Samarov,