| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1181710 | Chemometrics and Intelligent Laboratory Systems | 2007 | 6 Pages |
Abstract
We consider numerical characterization of DNA primary sequence based on the positions of bases (a, t, c, g) and the pairs of bases X, Y in DNA (X, Y = a, t, c, g). This leads to a representation of DNA by a numerical sequence. Then, we extract a novel invariant (molecular connectivity index) from the derived numerical sequences. The suitable invariant can offer a characterization of DNA primary sequence. Finally, we provide an illustration of its utility by making a comparison between ten DNA sequences belonging to β-globin gene in different species. The evolutionary relationships of ten species we have revealed in this contribution accord with phylogenetic tree properly.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bao-Hua Zhang, Hai-Shui Wang, Lu Xu,