Article ID Journal Published Year Pages File Type
1182047 Chinese Journal of Analytical Chemistry 2015 8 Pages PDF
Abstract

Capillary electrophoresis plays an irreplaceable role in the field of enzyme inhibitors screening with unique features of high-efficiency separation, short analysis time, minimal sample consumption, high sensitivity, ease to realize automatization etc. This review gives an overview of the applications of capillary electrophoresis in the field of enzyme inhibitors screening, and summarizes both the widely used off-line (pre-capillary) enzyme assay and on-line (in-capillary) enzyme assay. Finally, some future trends are briefly addressed.

Graphical abstractOwing to its unique advantages such as short analysis time, minimal sample consumption, ease of automatization and the high-efficiency separation mechanism, capillary electrophoresis are widely applied in enzyme inhibitors screening by pre-capillary and in-capilalry enzyme assay. This review summarized the recent progress and prospected the development trend of capillary electrophoresis in the field of enzyme inhibitors screening.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, , ,