Article ID Journal Published Year Pages File Type
1182205 Chinese Journal of Analytical Chemistry 2014 8 Pages PDF
Abstract

Biochemical analysis assays based on colorimetric methods using gold nanoparticles have many advantages such as high sensitivity, good selectivity, naked-eyes readout and complex instruments free. These methods have good prospects in applications. This review mainly focuses on colorimetric assays applying gold nanoparticles for biomolecules detection.

Graphical abstractThe determination (colorimetric and fluorometric) of AChE is based on RB-AuNPs. The well-dispersed RB-AuNPs (red) are induced to aggregate (purple) via electrostatic interaction in the presence of thiocholine derived from the hydrolysis of ATC catalyzed by AChE in the CSF of transgenic mice, accompanied with the fluorescence recovery of RB (the color of the stars changed from gray to green).Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, , , , , ,