Chemiluminescent Immunoassay and its Applications

Chemiluminescent immunoassay (CLIA) has been applied in different fields, including environmental monitoring, clinical diagnosis, food safety and pharmaceutical analysis, as a promising approach for selective, sensitive, rapid and simple analysis. It is often necessary to detect a large number of complicated or low-abundance samples. However, traditional methods need great consumption of time, reagents and labor, which limit their clinical applications. As a result, rapid, high-throughput, sensitive and low-cost detection methods have become the development trend of CLIA. In this review, we summarize the recent advances in CLIA and its applications in the last five years, and point out the future development of CLIA.