Development of Phase Separation Immunoassay

Phase separation immunoassay (PSI) combines some advantages of both homogeneous and heterogeneous immunoassays by means of a fast homogeneous immune reaction and a simple heterogeneous separation process. The method is readily amenable to automation. The principle of PSI is introduced. The carriers, the immobilization modes, the labels, the applications, and the prospect of PSI are comprehensively reviewed on the basis of 60 references cited.