Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1184687 | Food Chemistry | 2011 | 6 Pages |
Garlic oil (GO), rich in organosulphur compounds, has a variety of antimicrobial and antioxidant activities, however, its volatility and low physicochemical stability limit its application as food functional ingredients. The aim of this study was to investigate the physicochemical and release characterisation of inclusion complexes of GO in β-cyclodextrin (β-CD). The formation of GO/β-CD inclusion complex was demonstrated by different analytical techniques including Fourier transform-infrared spectroscopy, differential scanning calorimetry and X-ray diffractometry. The stoichiometry of the complex was 1:1. The calculated apparent stability constant of GO/β-CD complex was 1141 M−1, and the water solubility of GO was significantly improved by the phase solubility study. Furthermore, the release of GO from the inclusion complex was determined at a temperature range from 25 to 50 °C and in an acidic dissolution medium (pH 1.5), respectively. The release rate of GO from the inclusion complex was controlled.
Research highlights► A new process method to enhance physicochemical property of garlic oil was showed. ► Garlic oil could be efficiently complexed with β-CD to form an inclusion complex. ► The solubility and stability of garlic oil were increased by inclusion in β-CD. ► The release rate of garlic oil from the inclusion complex was controlled.