| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1192880 | International Journal of Mass Spectrometry | 2011 | 6 Pages |
Abstract
⺠We examined energy and entropy effects in dissociation of deprotonated peptides using surface-induced dissociation combined with RRKM modeling. ⺠Relative stability of peptides towards fragmentation is very different for protonated and deprotonated species. ⺠Fragmentation of acidic peptides is associated with very low threshold energy and tight transition state. ⺠Charge-remote fragmentation is observed for low-energy pathways of the basic RVYIHPF peptide. ⺠Backbone fragmentation is characterized by fairly high energy barrier.
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Authors
Julia Laskin, Zhibo Yang,