| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1192884 | International Journal of Mass Spectrometry | 2011 | 4 Pages |
The Heck reaction of isoprene with (p-iodophenyl)-trimethylammonium iodide was conducted in the gas phase. Relevant species of the catalytic cycle including the ionic product of the Pd-catalyzed coupling reaction were reliably characterized by exact ion mass measurements and by characteristic product ions generated by tandem-MS.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image ( K)Download as PowerPoint slideHighlights► Labile Heck coupling reaction intermediates and the coupling product are investigated in the gas phase. ► Charge-tagging, ESI-MSn, ion/molecule reactions and exact ion mass measurements are performed. ► A LTQ-Orbitrap Instrument is modified for the study. ► The results suggest that the Heck reaction proceeds via the accepted mechanism in solution and in the gas phase.
