Article ID Journal Published Year Pages File Type
1193539 International Journal of Mass Spectrometry 2012 7 Pages PDF
Abstract
► 2H- and 13C/15N-based peptides are comparable as quantitation standards for targeted mass spectrometry. ► Precision and accuracy for MRM-MS quantitation are not affected by the chromatographic isotope effect of 2H-based peptides. ► Cost benefit of 2H-based peptides allows for large-scale applications in targeted quantitative proteomics.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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