Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1193539 | International Journal of Mass Spectrometry | 2012 | 7 Pages |
Abstract
⺠2H- and 13C/15N-based peptides are comparable as quantitation standards for targeted mass spectrometry. ⺠Precision and accuracy for MRM-MS quantitation are not affected by the chromatographic isotope effect of 2H-based peptides. ⺠Cost benefit of 2H-based peptides allows for large-scale applications in targeted quantitative proteomics.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bekim Bajrami, Vahid Farrokhi, Mengtan Zhang, Ardit Shehu, Xudong Yao,