Article ID Journal Published Year Pages File Type
1194020 International Journal of Mass Spectrometry 2007 10 Pages PDF
Abstract

Theoretical techniques for optimizing the resolving power of TOF MS systems are presented, particularly for applications employing MALDI. These techniques are employed to design both a linear and a reflecting analyzer. Preliminary results on the performance of these instruments on proteins and peptides are presented, and compared with the theoretical predictions. Discrepancies between theory and experiment are analyzed, and further improvements are proposed.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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