Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1194201 | International Journal of Mass Spectrometry | 2007 | 8 Pages |
Abstract
A surface-normal surface-induced dissociation (SID) configuration specifically designed for coupling ion mobility spectrometry (IMS) and orthogonal time-of-flight (TOF) mass spectrometer is described. The instrument configuration and the effects of various operating parameters are critically evaluated using ion trajectory calculations (SIMION) and SID spectra of a series of model peptides. The utility of the instrument configuration for simultaneous acquisition of MS and MS–MS spectra in both data-dependent and non-data-dependent modes are also discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Wenjian Sun, Jody C. May, David H. Russell,