| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1195678 | Journal of the American Society for Mass Spectrometry | 2006 | 7 Pages |
Abstract
In this study, electrospray ionization mass spectrometry (ESI-MS) was used for the evaluation of the binding selectivity of a polyamide probe to single-base pair different DNA in an A·T-rich region. In this procedure, ΔIr(dsn) was introduced as a parameter to compare the binding affinities of the polyamides with the duplex DNA. The results show that ESI-MS is a very useful tool for analysis of binding selectivity of a polyamide probe to single-base pair different DNA.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Huihui Li, Gu Yuan,