Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1196487 | Journal of the American Society for Mass Spectrometry | 2007 | 5 Pages |
Abstract
A sample preparation method has been developed for detection of noncovalent protein–protein complexes by MALDI in this work. An aqueous solution of the matrix at pH 7 allows the reproducible detection of a protein dimer, a protein tetramer, and a heterodimer. The signals are stable under long irradiation and can be detected at wide ranges of concentrations and with different laser intensities.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Fenhong Song,