Article ID Journal Published Year Pages File Type
1196487 Journal of the American Society for Mass Spectrometry 2007 5 Pages PDF
Abstract

A sample preparation method has been developed for detection of noncovalent protein–protein complexes by MALDI in this work. An aqueous solution of the matrix at pH 7 allows the reproducible detection of a protein dimer, a protein tetramer, and a heterodimer. The signals are stable under long irradiation and can be detected at wide ranges of concentrations and with different laser intensities.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
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