Article ID Journal Published Year Pages File Type
1199154 Journal of Chromatography A 2014 14 Pages PDF
Abstract

•Ordered mesoporous silicas possess interesting potential for chromatographic applications.•These materials are used as support for chiral stationary phases in liquid chromatography.•These materials increase column capacity, separation selectivity and stability.

Recent advances in the development of new materials are having a major impact on analytical chemistry. For example, the unique properties of ordered mesoporous silicas (OMSs) have been shown to enhance the analytical performance of many existing techniques or allow new, exciting ones to be developed. Likewise, the introduction of organo-functional groups makes OMSs highly versatile and enables them to perform specialized tasks, such as the separation of chiral compounds. This review provides an overview with the most relevant achievements in the preparation of OMS particles functionalized with chiral selectors. In addition, some examples from the last fifteen years regarding the analytical applications of functionalized OMS for chiral separations by high-performance liquid chromatography, ultra-high pressure high-performance liquid chromatography and capillary electrochromatography have been reviewed.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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