| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1200123 | Journal of Chromatography A | 2014 | 8 Pages |
•A novel polymeric monolith was prepared by triallyl isocyanurate and trimethylolpropane triacrylate.•The column was successfully used as the stationary phases of HPLC and CLC, respectively.•Successfully separate the mixture of small molecules compounds by RP-HPLC.•The column performed 124,348 theoretical plates per meter for p-xylene.
A new polymeric monolith was prepared in stainless-steel column and fused-silica capillary, respectively, by atom transfer radical polymerization technique. In the polymerization, triallyl isocyanurate (TAIC) was used as the functional monomer; trimethylolpropane triacrylate (TMPTA) as the crosslinking agent; polyethylene glycol 200 and 1,2-propanediol as the co-porogens; carbon tetrachloride as the initiator and ferrous chloride as the catalyst. The conditions of polymerization were optimized. Morphology of the prepared poly(TAIC-co-TMPTA) monolith was investigated by scanning electron microscopy; pore properties were assayed by mercury porosimetry and nitrogen adsorption. The characterization indicated that the prepared reversed-phase monolith possessed uniform structure, good permeability and mechanical stability. The column was used as the stationary phase of reversed phase high performance liquid chromatography (RP-HPLC) and capillary liquid chromatography (CLC) to separate the mixture of aromatic compounds. The new column performed around 125,000 theoretical plates per meter. The column showed good reproducibility: the relative standard deviation values of the retention factor values for aromatic compounds were less than 1.52% (n = 7, column-to-column).
