Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1200604 | Journal of Chromatography A | 2012 | 11 Pages |
Abstract
⺠The effect of the counterion on the elution of a polypeptide is investigated. ⺠A retention model based on the counterion binding to the peptide charges is proposed. ⺠The model is validated through two independent sets of experiments. ⺠The model developed can be used for preparative process optimization.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
David Gétaz, Subrahmaniam B. Hariharan, Alessandro Butté, Massimo Morbidelli,