Article ID Journal Published Year Pages File Type
1201788 Journal of Chromatography A 2012 11 Pages PDF
Abstract
► We apply zwitterionic stationary phases for chiral separations of small peptides. ► Enantiomers of the all-l/all-d type and d/l sequence isomers are separated. ► Retention depends on efficient simultaneous double ion pairing. ► H bonding with the peptide backbone strongly contributes to chiral recognition. ► Combination of structural features of peptide and selector determines outcome.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, ,